Endocrine Abstracts

Introduction: Primary aldosteronism (PA) is widely recognized as the most common form of secondary hypertension (1). PA, also known as Conn syndrome, is a group of pathological conditions associated with an aldosterone secretion inappropriate for sodium intake, that is relatively autonomous from renin–angiotensin system activity and potassium levels.Clinical Case 1: Thirty two year-old patient, diagnosed since 11 months with arterial hypertension wi...

Introduction: Paragangliomas (PGL) are rare neuroendocrine tumors of the chromaffin cells of the sympathic and parasympathic ganglia. They are responsible for catecholaminergic hypersecretion syndrome. Clinical presentation and malignant potential are variable and closely linked to the genetic profile.Clinical Case 1: Fifty three year old patient, diagnosed with diabetes and high blood pression for 4 years, she reported a Menard’s Triad evolving for...

Introduction: Craniopharyngioma (CP) is a rare epithelial tumor of the sellar and suprasellar region, histologically of low grade (WHO grade I). Significant locoregional invasion explains the frequency of recurrence, mainly due to incomplete surgical resection. We report two cases of craniopharyngioma in children, in order to outline the therapeutic difficulties encountered during management.Case 1: Eleven years-old patient reported frontal headache with...

Introduction: Chronic excess of growth hormone is responsible for numerous cardiovascular, respiratory, metabolic and neoplastic complications, leading to significant morbidity and mortality. The aim of this study is to analyze the different cardiovascular manifestations and cardiovascular risk factors in acromegaly.Methods: A retrospective descriptive study including 44 patients hospitalized in the endocrinology department of University Hospital Mohamed...

Introduction: Hyperprolactinemia may be associated with weight gain, metabolic syndrome, and insulin resistance. Treatment with dopamine agonists (DA) has been shown to reduce body weight and improve metabolic parameters. The objective of our study is to confirm weight gain secondary to hyperprolactinemia and analyze the evolution of weight in patients under dopaminergic antagonists. Materials and Methods: This is a prospective cross-sectional analytical...

Introduction: Thyroid storm (TS) is a severe manifestation of thyrotoxicosis, (1). It is most commonly seen in Graves’ disease and can occur due to a non-compliance to anti-thyroid medications Management includes both addressing end organ damage and attaining a euthyroid state. We report the case of a patient who presented a thyroid storm complicating a grave’s disease and unmasking, during its management, a corticotropic insufficiency.Clinical...

Introduction: The association of multi-organ autoimmune diseases is described. We report a case of association between Latent autoimmune diabetes in adults (LADA) and systemic scleroderma (SSc), which remains a rarely reported entity in the literature.Observation: 38-year-old female patient, followed for systemic scleroderma with digestive and pulmonary involvements. The patient presented a dysphagia to solids with dyspnea installed in the last 2 months,...

Introduction: Adrenal insufficiency is rarely diagnosed during pregnancy. In the absence of treatment it is associated with high maternal-foetal morbidity and mortality. We report the case of a twenty-one years old female patient, diagnosed with adrenal insufficiency during a diabetic pregnancy of 12 weeks of gestation.Observation: Twenty-one years old female patient, diagnosed with type 1 diabetes since the age of 15, Referred to our department for the ...

Introduction: Mitochondrial diabetes represents about 1% of diabetes but still very often misunderstood. The most frequent mutation is 3243A >G of the mtDNA, which is responsible for the maternally inherited diabetes and deafness syndrome (MIDD). We report an observation of a patient with strong suspicion of mitochondrial diabetes.Case presentation: 43-year-old female patient, with diabetes for 5 years on an Insulin Therapy.Anamnesis:&hypen;&...

Introduction: Metabolic disorders are a relevant cause of morbidity and disability in patients with Cushing’s syndrome (CS) even after a successful treatment. The aim of our study was to assess the prevalence of metabolic syndrome in our CS patients, as central obesity, dyslipidemia, diabetes, and hypertension, and to discuss the main adverse effects of CS on metabolism and emphasize the importance of long-term monitoring and treatment of these complications.Patients and ...